Brain Diseases
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Jan Drew may be called by the CDC to investigate another case of Mad Amalgam Disease (MAD)
(13 Messages)
Posted on Wed, Jan. 07, 2004 In N.J., a link to mad cow? Seven who apparently died of a similar illness are getting new attention. By Faye Flam Inquirer Staff Writer Although U.S. health officials say no one has gotten mad cow disease from American beef, a Cinnaminson woman says seven people died of a closely related disease after eating at the Garden State Race Track in Cherry Hill. The seven apparently died of sporadic Creutzfeldt-Jakob disease, a fatal brain-wasting malady, according to a spo ...
UK - Pollutants cause huge rise in brain diseases
(11 Messages)
[ Subject: UK: Pollutants cause huge rise in brain diseases [ From: "Tim Murphy" <i...@cinox.demon.co.uk> [ Date: 15 Aug 2004 04:45:09 -0500 Sunday August 15, 2004 The Observer (UK) Pollutants cause huge rise in brain diseases Scientists alarmed as number of cases triples in 20 years Juliette Jowit, by environment editor The numbers of sufferers of brain diseases, including Alzheimer's, Parkinson's and motor neurone disease, have soared across the West in less than 20 years, scie ...
Manic Depression is a brain disease in the same category as
(13 Messages)
Manic Depression is a brain disease in the same category as Alzheimer's, Parkinson's, and Multiple Sclerosis. These four diseases have the following in common: 1. The cause is unknown. 2. There is no definitive diagnostic test. 3. They are diagnosed primarily by presentation of symptoms. 4. They respond to medication treatments. 5. They cost society a lot of money.
OT: Surgical instruments spreading brain wasting disease
(12 Messages)
Holy shit! I had no idea that any kind of pathogen could survive the sterilization process that is normally used on surgical instruments. As it turns out, prions that cause Creutzfeldt-Jakob disease are not killed by steam sterilization, thus instruments used on a patient with this disease are capable of spreading the disease to every person who undergoes surgery with the same set of instruments. Teresa - wondering how these prions can be killed? ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Brain malady ...
Sites
Paul Thompson's Research Publications Atlas Construction. To create the Alzheimer's Disease atlas, high-resolution 3D (256x256x124 resolution) T1-weighted fast SPGR (spoiled GRASS) magnetic resonance imaging (MRI) volumes were acquired from 26 subjects diagnosed with mild to moderate Alzheimer's Disease (NINCDS-ADRDA criteria), and 20 control subjects matched for age, gender, educational level and handedness. Connected systems of parametric surface meshes [1] were used to model 84 structures per brain: 16 deep sulcal, callosal and hippocampal surfaces, all major cortical sulci, Sylvian fissures, 14 ventricular ...
Results. A mosaic of variability patterns emerged, which segregated sharply according to the functional specialization of each system. Sharp contrasts in variability and asymmetry were observed between hippocampal and periventricular anatomy, and between heteromodal and idiotypic cortex. Fundamental patterns of structural variability in the Alzheimer's disease brain were identified. From an imaging standpoint, registration algorithms were evaluated to determine their ability to reduce anatomic variation across the 84 structures. By tuning algorithm parameters and characteristics of the target atlas template, criteria were ...
MedlinePlus: Genetic Brain Disorders Some genetic brain disorders are due to random gene mutations or mutations caused by environmental exposure, such as cigarette smoke. Other disorders are inherited, which means that a mutated gene or group of genes is passed down through a family. Still other disorders are due to a combination of genetic changes and other outside factors. Some examples of genetic brain disorders include leukodystrophies , phenylketonuria , Tay-Sachs disease , and Wilson disease .
The Dana Foundation - BrainWeb BrainWeb provides information and links to validated sites about brain diseases and disorders. These include outside resources reviewed by scientific advisors, as well as articles in Dana publications. The listing of an organization's Web site does not imply endorsement by the Dana Foundation or the Dana Alliance for Brain Initiatives. The information provided is not a substitute for medical advice; be sure to consult your doctor for diagnosis and treatment.
Brain aneurysm, cerebral vasospasm, arteriovenous malformation (AVM This is a Website dedicated to promoting public awareness of diseases of brain blood vessels, including brain aneurysm , cerebral vasospasm, arteriovenous malformation or AVM , carotid artery disease, cavernous malformation or cavernoma , venous angioma , and more. The Site comprehensively covers both patient-care and research aspects of many brain vascular disorders including brain aneurysm , AVM and cavernoma . It is intended to be a valuable resource for brain surgery, brain aneurysm , and brain hemorrhage patients and their families, and also for physicians and allied health specialists interested in brain ...
News
Positive Kuvan(TM) Pivotal Phase 3 Trial Results Published in The The patients were randomly assigned to receive placebo or 10 mg/kg of Kuvan daily for six weeks. Patients were evaluated every two weeks for changes in blood Phe levels and adverse events. The primary objective was to assess the efficacy of Kuvan compared with placebo for reduction of blood phenylalanine in patients with PKU. The secondary objective was to assess the safety of Kuvan compared with placebo. A total of 87 patients completed six weeks of treatment.
Kuvan is an investigational oral small molecule therapeutic for the treatment of PKU. The active ingredient in Kuvan, sapropterin dihydrochloride, is the synthetic form of 6R-BH4 (tetrahydrobiopterin), a naturally occurring enzyme cofactor that works in conjunction with phenylalanine hydroxylase (PAH) to metabolize Phe. Clinical data suggest that treatment with Kuvan results in significant reductions in blood Phe levels in BH4-responsive patients. It also may enable some patients to minimize or eliminate highly-restrictive dietary constraints by increasing Phe tolerance levels. BioMarin and Merck Serono estimate ...
Neuren buys into brain disorder drug Neuren chief executive David Clarke said the deal had the full backing of the company's board. "We've got a late-stage pre-clinical asset in a field that we know very well that we've purchased for a very cost-effective price, with two new shareholders who give the firm a great deal of international credibility." Clarke said Motiva had proven effectiveness in phase II trials for a broad range of cognitive deficits but Neuren planned to run another trial to prove definitively the drug could be targeted at post-stroke depression. The initial payment of US$4.4 million ...
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HIV patients likely to get brain diseases Today's National Coverage DELETE ME Toddler dies of influenza Parents search for answers Victim Jasmin lived nearby Woman judge to join top court Reserve paves way for another rate rise Security agencies tongue-tied Hospital conflict of interest denied Student group spent $500,000 without documents, audit finds Former government adviser warns against voter backlash Plea for intervention to be eased National Index
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Blogs
Drug Addiction and Alcoholism: A Disease Estimates say 18,000,000 people need alcohol treatment, another 5,000,000 need drug treatment, and less than 1 in 4 will get it More than 50% of adults arrested for major crimes tested positive for drugs. More than 75% of female victims of domestic violence report their assailant was using drugs or drinking. Health care costs are double for drinkers as opposed to non-drinkers. Drug related deaths have doubled since early in the 1980's. Alcohol and drug abuse in the family is a factor in 3 out of 4 cases of children entering foster care
The following is a very well written article on the disease of addiction. While not everyone agrees with the concept of addiction as a disease, it is the most accepted view in the United States, and has been for years. Addiction is a brain disease, with identifiable symptoms, signs and progression. Still, the most important concept from a treatment view is the single concept "Is your continued use causing problems, and are you having trouble stopping?" Here is the article on the disease of addiction . By Jonathan Huttner The entire concept of addiction has suffered greatly from a misconception on the part ...
Research brings hope of curing brain disease Health Warnings! Is this list of news items comprehensive? -- No! This list is not comprehensive. We don't aim to provide comprehensive news coverage, but we do try to identify items which may of interest to those interested in neurology, neuroscience and related areas. Are all of the news stories trustworthy? -- No! These news stories are not always trustworthy! We don't assess the quality of the reporting. You should always critically appraise any item included here.
Research brings hope of curing brain disease - Reported in The Guardian . Scientists have developed a revolutionary new treatment for neurological diseases that uses an injection to tweak the way genes work in the brain. The research raises hopes for a new era of effective treatments for some of the most debilitating - and so far incurable - brain conditions, including cancer and Alzheimer's disease. Tests of the therapy at Harvard Medical School in Boston found that a simple injection was able to cure mice of a potentially fatal brain disease. The researchers behind the breakthrough, led by Professor Manjunath Swamy, ...
Exercise Helps Improve Schizophrenia WASHINGTON: Mental and physical exercise can help improve behavioural deficits in schizophrenia and repair damaged chemical transmitter pathways in the brain, a new study by researchers in Australia has shown. The study, carried it out on a mouse model, was conducted by researchers at Melbourne’s Howard Florey Institute in collaboration with a team from Mental Health Research Institute of Victoria. As a part of their study researchers led by Dr Anthony Hannan, Dr Caitlin McOmish, and Emma Burrows characterised a genetically altered mouse and discovered that it had schizophrenia-like behaviours, including learning and memory problems, ...
Hope of cure for fatal brain diseases SCIENTISTS HAVE developed a revolutionary new treatment for neurological diseases that uses an injection to tweak the way genes work in the brain. The research raises hopes for a new era of effective treatments for some of the most debilitating - and so far incurable - brain conditions, including cancer and Alzheimer's disease. Tests of the therapy at Harvard Medical School in Boston found that a simple injection was able to cure mice of a potentially fatal brain disease. The re- searchers behind the breakthrough are planning further tests and expect to conduct human trials within five years. The team ...